Publications

1. Gemechu Y, Lemecha M.
Genetic disruption of hnRNPI reveals a microbial-metabolic axis in colitis-associated cancer. AJP-Gastrointestinal and Liver Physiology. 2025 Aug 1;329(2):G360-G362.

https://doi.org/10.1152/ajpgi.00236.2025

 

​2. Lemecha M., Chalise JP, Takamuku Y, Zhang G, Yamakawa T, Larson G, Itakura K.
Lcn2 mediates adipocyte‑muscle‑tumor communication and hypothermia in pancreatic cancer cachexia. Molecular Metabolism. 2022;66:101612.

DOI: 10.1016/j.molmet.2022.101612

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3. Lemecha M., Morino K, Imamura T, Iwasaki H, Ohashi N, Ida S, Sato D, Osamu S, Satoshi U, Maegawa H.
MiR‑494‑3p regulates mitochondrial biogenesis and thermogenesis through PGC1‑α signaling in beige adipocytes. Scientific Reports. 2018;8:15096.DOI: 10.1038/s41598-018-33438-3

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4. Lemecha M., Huang R, Ehsani A, Zhang G, Halise JP, Whitson RH, Itakura K.
Role of Arid5b in Thermogenesis and Adipose Tissue Browning. Diabetes. 2021 Jun;70(Suppl 1):DB21‑34‑OR. (Conference abstract).  https://doi.org/10.2337/db21-34-OR

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5. Lemecha M., Morino K, Seifu D, Imamura T, Nakagawa F, Nagata A, et al.
Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation. PLoS ONE. 2018;13(8):e0201661.

DOI: 10.1371/journal.pone.0201661

 

6. Chalise J, Ehsani A, Lemecha M., Hung YW, Zhang G, Larson G, Itakura K.
ARID5B regulates fatty acid metabolism and proliferation at the Pre‑B cell stage during B cell development. Frontiers in Immunology. 2023;14:1113823.

DOI: 10.3389/fimmu.2023.1170475

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7. Lim JE, Sargur Madabushi S, Vishwasrao P, Song JY, Abdelhamid AMH, Ghimire H, Vanishree VL, Lamba JK, Dandapani S, Salhotra A, Lemecha M., Pierini A, Zhao D, Storme G, Holtan S, Aristei C, Schaue D, Al Malki M, Hui SK.
Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old mice. Frontiers in Oncology. 2022 Nov 10;12:1045016.

DOI: 10.3389/fonc.2022.1045016

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8. Iwasaki H, Ichihara Y, Morino K, Lemecha M., et al.
MicroRNA‑494‑3p inhibits formation of fast oxidative muscle fibres by targeting E1A‑binding protein p300 in human‑induced pluripotent stem cells. Scientific Reports. 2021;11:1161.

DOI: 10.1038/s41598-020-80742-y

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9. Okamoto T, Morino K, Ugi S, Nakagawa F, Lemecha M., Ida S, Ohashi N, Sato D, Fujita Y, Maegawa H.
Microbiome potentiates endurance exercise through intestinal acetate production. AJP‑Endocrinology and Metabolism. 2019;316(6):E956–E966. DOI: 10.1152/ajpendo.00510.2018

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10. Murata K, Morino K, Ida S, Ohashi N, Lemecha M., Park SY, Ishikado A, Kume S, Choi CS, Sekine O, Ugi S, Maegawa H.
Lack of O‑GlcNAcylation enhances exercise‑dependent glucose utilization potentially through AMP‑activated protein kinase activation in skeletal muscle. BBRC. 2018;495(2):2098–2104.   DOI: 10.1016/j.bbrc.2017.12.081

 

11. Ohashi N, Morino K, Ida S, Sekine O, Lemecha M., Kume S, Park SY, Choi CS, Ugi S, Maegawa H.
Pivotal role of O‑GlcNAc modification in cold‑induced thermogenesis by brown adipose tissue through mitochondrial biogenesis. Diabetes. 2017;66(9):2351–2362.  DOI: 10.2337/db16-1427

 

12. Hirotaka Y, Katsutaro M, Lemecha M., Taishi I, Kohei K, Takao I, Hiroshi M.
Amla enhances mitochondrial spare respiratory capacity by increasing mitochondrial biogenesis and antioxidant systems in a murine skeletal muscle cell line. Oxidative Medicine and Cellular Longevity. 2016;2016:6728490.

DOI: 10.1155/2016/1735841

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13. Takamuku Y, Lemecha M., Itakura K.

Differential growth of pancreatic ductal adenocarcinoma cells in serum amyloid A (SAA) deficient mouse model through immune modulation. Cancer Research. 2024 Jan;84(2_Supplement):C031.

https://doi.org/10.1158/1538-7445.PANCA2023-C031

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14. Lim JE, Sargur Madabushi S, Lemecha M Shukare, Ghimire H, Paredes J, Mokhtari S, Sanchez JF, Sandhu KS, Salhotra A, Nakamura R, Wong J, Stein AS, Schaue D, van den Brink MRM, Al Malki MM, Storme G, Hui S.
Tissue‑Specific Myeloablative Conditioning with Total Marrow Irradiation Enhances Gut Microbiome Diversity and Mitigates GvHD: A Novel Therapeutic Approach. Blood. 2023;144(Supplement 1):Abstract 3393. (Conference abstract).  https://doi.org/10.1182/blood-2024-210774